Back, Muscle and Joint Pain Specialists

Call: 01908 604 666

Prolotherapy

Prolotherapy

Prolotherapy injections work by stimulating the body to make new collagen fibres that are laid down within the substance of the ligaments, thickening and strengthening them.  The solution injected is hypertonic dextrose or occasionally a solution is used containing dextrose, glycerol and 1% phenol. The solution provokes inflammation which attracts collagen producing cells, resulting in a thicker and healthier collagen fibres. This strengthens the ligaments and stops them from being too loose, stabilising the spine or peripheral joints injected.

Conditions treated by Prolotherapy

Prolotherapy is used to treat ligaments that have become loosened or stretched from over use or injury or as a result of a physical condition such as Ehlers Danlos Syndrome.  Ligaments provide stability to joints and if they become loose the joint can become unstable and painful. Prolotherapy is appropriate for low back pain and for many other joints in the body such as the knee, shoulder or ankle. At Blackberry Clinic we have had some success with patients with Ehlers Danlos syndrome, alleviating the symptoms of joint hypermobility.   The injection  solution used is used widely in America and is produced by licensed manufacturers in the UK. There is clinical research that endorses its safety and effectiveness as a treatment. For further information see our FAQ’s or please ask the doctor during your consultation. 

Frequently asked questions about Prolotherapy

You will have a thorough assessment to see which treatment is appropriate and the treatment will be explained to you.  You will be taken to our fluoroscopy theatre so the doctor can use the x ray or ultrasound equipment for guidance in placing the needle. The doctor will explain what is happening throughout the procedure.

A local anaesthetic will be used to reduce the pain and there are other methods of pain relief available if necessary.  These injections do cause some aching and stiffness for one to two days. The benefit is gradual and should be optimal after 6-8 weeks.

Prolotherapy is a course of three injections at intervals of between one to three weeks. A second course can be used if there is a significant but incomplete effect from the first.

Our Musculoskeletal (MSK) Doctors are experienced in these injections. See below for Doctors who offer these procedures and the Clinics where they work.

Please make a double appointment (same cost as a single consultation) with the doctor who you have been referred to (costs are available here)  He/she will then take a history, examine you and make a diagnosis and recommendation. He/she can also write to your GP.

If Prolotherapy is determined to be the appropriate course of treatment then you will need to make 3 further appointments at weekly intervals at a cost outlined here.

The injections are done under x-ray guidance and take about 3 minutes within your 30 minute appointment (Sometimes, if the pain is severe, he/she may advise a cortisone injection first which costs £350-500 depending on the site. You will then need to leave 2 weeks before starting prolotherapy)

We hope that answers all of your queries. If not, please contact our theatre staff at the clinic in Milton Keynes on 01908 604666.

Please bring  the most recent MRI scan and report if possible.

 The use of hypertonic dextrose solutions to treat lax ligaments and instability of any joints in the body. Platelet Rich Plasma and Stem cell therapy also count as prolotherapy since the result is a ‘proliferation’ of normal body connective tissue and collagen found in ligaments and tendons.

A standard set of prolotherapy in the UK is three injections but if there is considerable improvement and the improvement is incomplete then a further three injections are frequently offered.

On average, patients experience one year of improvement and relief from prolotherapy. However, there is a huge variation and sometimes improvement lasts from three months to 15 years. A repeat course of injections is often indicated and produces a similar period of relief.

 We do not offer intravenous sedation but we do have Entenox gas,  a mixture of nitrous oxide and oxygen,  which provides an element of pain relief and sedation. Some patients who are already taking muscle relaxants such as Diazepam can take a tablet prior to one hour before their treatment. Most patients do not find that either of these measures is necessary since the discomfort is usually tolerated sufficiently. 

About 80% of patients experience at least a 50% improvement in the symptoms.

If you call the Blackberry  Clinic of your choice you will find that most appointments are available within the week depending upon your own availability

 Yes, but the fluoroscopic x-ray is extremely low dose, you get more radiation on a transatlantic flight! For accuracy we use fluoroscopic x ray. 

 There is minimal danger to the sciatic nerve. The risk may be more if the injection is done without x-ray guidance. There is 1:7000 chance of allergy, infection bleeding or nerve damage as with any spinal injection.

Yes, we use a number of different solutions and techniques depending upon the problem being treated. Commonly used preparations include:

Dextrose: 5%. 15% and 25%

P2G: which contains dextrose 12.5% glycerol 12.5% and phenol 1%.

Posterior SI ligaments, interosseus and occasionally sacro-tuberous and sacro-spinous ligaments.

Currently Blackberry Clinic Milton Keynes and Blackberry Clinic Oxford.

Prolotherapy can be used to treat the spine including lumbar, thoracic and cervical spine up to the level of C2 but we do not use this treatment any higher.

We can treat osteoarthritis of the knee and hip along with recurrent ankle sprains and shoulder instability or rotator cuff tendinopathy.

There are too many areas of the body to list here and it is worth a consultation to discuss your options.

For a standard set of 3 injections (done on three appointments from 1-4 weeks apart) the cost is £350 per treatment so a standard set is £1050.

In private hospitals these types of injections can cost £1500 per time!!

Yes, for safety and accuracy whilst maintaining the comprehensive nature of the treatment.

 There is no limit, but if you needed more than 3 courses in a year you may have to reassess the appropriateness of the treatment.

Yes, our theatre staff will assess you after the treatment and so long as you are feeling fine they will let you go within 20 minutes of finishing the procedure.

Yes, so long as you were doing those things before the injection without much discomfort. We like you to avoid provocative activity (ie activity that usually caused your pain) until 3-4 weeks after the course has finished.

Yes, so long as you were doing those things before the injection without much discomfort you can start these activities again shortly after your treatment. Check with the nurse or doctor. 

Yes, please stop non-steroidal anti-inflammatory medication such as Nurofen, Ibuprofen, Naproxen and Diclofenac on the day of the procedure and do not resume until after the course has finished. Please discuss with the doctor at the first appointment. We suggest you stop Turmeric too.

 Usually one area of the body is treated at one visit.

Both sacroiliac joints can be treated on the same visit, this can include the lumbar spine also.

No more than 3 levels of the lumbar spine are treated at one visit.

A short letter from the podiatrist would be fine.

It is guided by fluoroscopic x-ray for safety and efficacy, there is no need for contrast/dye.

We assess the full effect 4-6 weeks after the last of the three injections. However some patients feel a beneficial effect after the first injection.

The frequency of subluxation/dislocation should diminish as you progress through the process.

The waiting list can be 1 day to 2 weeks depending on various circumstances but it is worth calling to find out the current wait.

1/7000 chance of allergic reaction, infection, bleeding or nerve injury which is similar to any spinal injection.

 1/7000 chance of allergic reaction, infection, bleeding or nerve injury which is similar to any spinal injection.

The pain can feel worse for a day or so after the injection.

Clinicians offering Prolotherapy

  • All
  • Aberdeen
  • Brighton
  • Croydon
  • Exeter
  • Guildford
  • Fareham
  • Ipswich
  • Lichfield
  • Milton Keynes
  • Oxford
  • Birmingham
  • Worcestor
All
  • All
  • Aberdeen
  • Brighton
  • Croydon
  • Exeter
  • Guildford
  • Fareham
  • Ipswich
  • Lichfield
  • Milton Keynes
  • Oxford
  • Birmingham
  • Worcestor
simon petrides

Dr Simon Petrides

Medical Director, Musculoskeletal & Sports Medicine Doctor
Milton Keynes

Dr Tom Saw

Musculoskeletal & Sports Medicine Doctor
Oxford & Birmingham

Dr Jonathan Korgaonkar

Sport & Exercise Medicine Consultant
Oxford

Brinda Christopher

Consultant in Sport, Exercise and Musculoskeletal Medicine
Milton Keynes

Dr Raymond Leung

Consultant in Sport & Exercise Medicine
Milton Keynes

Make an Appointment

Prolotherapy Related Resources

Sport and Exercise Medicine at Blackberry Clinics

We have Sport & Exercise Medicine Doctors at a number of our Blackberry Clinics nationwide. These specialist doctors offer a comprehensive service for many painful …

READ MORE

How do you manage chronic pain?

At Blackberry Clinic we believe that a multi disciplinary patient centred approach is key to pain management. Our doctors and practitioners work together to produce …

READ MORE

Dr Petrides lectures for Royal College of Podiatry

Dr Simon Petrides is pleased to have been invited to present a lecture at the inaugural National  Conference held by the newly formed Royal College of Podiatry at the ACC Convention Centre in Liverpool

READ MORE

What are pain coping skills?

At Blackberry Clinic we specialise in the treatment of acute and chronic pain caused by musculoskeletal conditions such as arthritis and back, muscle and joint …

READ MORE

How can I relieve back pain in pregnancy?

At Blackberry Clinic we often see pregnant women who are suffering from back pain. There are gentle and effective treatments available from our chiropractors, physios …

READ MORE

What is the treatment for SI joint pain?

In order to find out what treatment is needed a diagnosis must be made for the best outcome. HOW IS A DIAGNOSIS MADE? A physiotherapist, …

READ MORE

Spotlight on spinal stenosis

At Blackberry Clinic our doctors and therapists treat acute and chronic back pain. Key to the best outcome is a diagnosis of where the back …

READ MORE

What does sacroiliac joint pain feel like?

Chronic low back pain can have a dramatic impact on daily activities as well as the ability to work and exercise. The sacroiliac joint (SIJ) …

READ MORE

Blackberry Clinic Birmingham opening 19th April!

Our new clinic is open for treatments from the 19th April and we have pain clinic appointments available.   We are delighted to have this …

READ MORE

Blackberry Clinic Birmingham will open in April!

Our business development manager, Oli Petrides, and our compliance officer, Luke Owen, have been working this new venture and we are delighted to say that …

READ MORE

‘Chronic Pain Management’ – Dr Balasubramanian

At Blackberry Clinic our pain management and pain clinic consultants are experts in their field. Dr Shyam Balasubramanian has co-authored ‘Chronic Pain Management’ for doctors …

READ MORE

The Pain-Free Mindset -Author- Dr Deepak Ravindran

We are delighted that one of our interventional pain medicine doctors has written a book using his extensive experience in acute and chronic pain management. …

READ MORE

New team member for Oxford- Dr Jonathan Korgaonkar

Dr Jonathan Korgaonkar FFSEM(UK) MBBS MSc MRCGP PGCert   Sport & Exercise Medicine Consultant We are delighted to welcome Dr Jonathan Korgaonkar to the Blackberry …

READ MORE

Prevention is better than cure – low back pain

At Blackberry Clinic the most common condition treated by our doctors and therapists is low back pain. Indeed, this is a condition in which we …

READ MORE

What is the difference between Prolotherapy, PRP and Prolozone?

At Blackberry Clinic we have a Pain Clinic service run by expert Pain Management and Musculoskeletal Medicine doctors  who use a variety of regenerative medicine …

READ MORE

Welcome to Dr Rangu Iyer!

We are delighted to welcome Dr Rangu (Ranganathan) Iyer to Blackberry Clinic Havant. He is a Pain Management and Musculoskeletal Medicine Consultant with over  38 …

READ MORE

Private MSK Pain Clinic – what do we do?

Blackberry Clinics  offer private Musculoskeletal Medicine (MSK) Clinic treatments including spinal injections such as epidurals for slipped/prolapsed disc, caudal epidurals, and nerve root blocks. Our …

READ MORE

Spotlight on Knee Pain – Quadriceps Tendinopathy

The quadriceps tendon attaches your quadriceps muscles to your kneecap (patella). It works to straighten your knee and helps you walk, jump, and climb stairs.

READ MORE

Blackberry Clinic Tips – Avoid common Cycling injuries

There are two main types of cycling injury, those caused by falling off (which we don’t discuss below) and the issues caused by overtraining, biomechanical …

READ MORE

Spotlight on Musculoskeletal Medicine

Musculoskeletal Medicine (MSK Medicine) is a specialised medical field dealing with the diagnosis and treatment of problems arising from the musculoskeletal system. This includes injuries …

READ MORE

Blackberry Clinic Pain Clinic appointments available

We offer a Pain Clinic Service at various Blackberry Clinics. Our flagship Blackberry Clinic Milton Keynes has a large team of Pain Clinic Doctors who …

READ MORE

Iliotibial Band Syndrome – Advice for Runners

  WHAT CAN BLACKBERRY CLINIC DO TO HELP RUNNERS WITH ILIO TIBIAL BAND SYNDROME? At Blackberry Clinic we have the expertise to offer accurate diagnosis …

READ MORE

Spotlight on Ehlers Danlos Syndrome and Prolotherapy

Ehlers-Danlos syndrome (EDS)  is a group of inherited conditions mostly affecting the connective tissue in the body. These tissues help support the ligaments, tendons, blood …

READ MORE

Myths about Chronic Pain and The Strain of Pain

At Blackberry Clinic we pride ourselves on offering patients with acute and chronic pain treatments they may not have been offered elsewhere. At the heart …

READ MORE

You don’t have to play tennis to get tennis elbow!

If you are told you have tennis elbow you may feel baffled if you have never picked up a tennis racket in your life! However, …

READ MORE

Focus on Runner’s Knee

Patellofemoral pain (runner’s knee) is the most common overuse injury among runners. It is the term used by medical practitioners when pain occurs at the …

READ MORE

Blackberry Clinic Oxford Open!

We are delighted to announce that Blackberry Clinic Oxford has reopened. Dr Tom Saw and Dr Tham Wedatilake are available for Musculoskeletal Medicine, Sport & …

READ MORE

Prolotherapy Research Articles

Prolotherapy for back or neck pain consists of a series of injections of an irritant, usually a dextrose based compound, into the supporting intervertebral ligaments.

READ MORE

32 years and going strong!

Thanks to Linkedin Dr Simon Petrides was reminded this week that it is his ‘workanniversary’ and he that has been running the Blackberry Clinic for …

READ MORE

Back Pain in Swimmers

With the news that swimming pools are going to be opened again this summer following the lockdown for Covid-19 here is some timely information about …

READ MORE

Patellofemoral Pain Syndrome

Patellofemoral pain (runner’s knee) is the most common overuse injury among runners. It is the term used by medical practitioners when pain occurs at the …

READ MORE

Prolotherapy FAQs with Dr Simon Petrides

What is prolotherapy?  The use of hypertonic dextrose solutions to treat lax ligaments and instability of any joints in the body. Platelet Rich Plasma and Stem …

READ MORE

Facts about Fibromyalgia

Fibromyalgia is a chronic condition causing widespread pain and profound fatigue. The pain tends to be felt as diffuse aching or burning, often described as …

READ MORE

Cervical Facet Joint Irritation can be a Real Pain in the Neck!

Cervical facet joint pain is due to the irritation of the cervical facet joints. These are the joints at the posterior (back) aspect of the spine.

READ MORE

Dr Simon Petrides answers your questions about Prolotherapy

These are some of the questions that we get asked frequently by our patients enquiring about prolotherapy at Blackberry Clinic. I hope this list helps …

READ MORE

Go the Glasgow Mile -BASEM Conference 2019

This year’s British Association of Sport and Exercise Medicine Conference in Glasgow was well attended and full of the county’s leading experts in Sport & …

READ MORE

PRP – Platelet Rich Plasma

PRP or Platelet-Rich Plasma is derived from a blood sample taken from a vein in your arm. It is spun down in a centrifuge and the portion with the most platelets

READ MORE

Hackett Hemwall Patterson Foundation Prolotherapy Conference

Dr Simon Petrides our Medical Director and a group of Musculoskeletal physicians and Sport and Exercise Medicine physicians from the Blackberry Clinic, visited Budapest in May 2019 for the Hackett Hemwall Patterson foundation prolotherapy conference at the Pain School International conference.

READ MORE

Rugby Injuries

Rugby Union is a high velocity, collision sport, so it comes as no surprise that it reports one of the highest rates of injuries in team sports (Brooks, 2005). As the game becomes faster and the players get stronger, it is predicted that the injury rate will rise.

READ MORE

Neurogenic hamstring and calf pain in football. When is a tear not a tear?

Hamstring and calf injuries or strains are one of the most difficult conditions to treat in sports medicine. They are especially common in footballers but also found in the general population due to an increase in activity levels.

READ MORE

Discogenic low back pain

Discogenic low back pain (DLBP) accounts for 39% of chronic lower back pain (CLBP). Unfortunately, accurate diagnosis remains challenging, as clinical examination and magnetic resonance imaging (MRI) may be normal. Provocative Discography (PD) is one method of distinguishing DLBP from other back pain causes.

READ MORE

New Research into Prolotherapy

A new research study by Dr James Inklebarger and our Clinic Director, Dr Simon Petrides has been recently published in the Journal of Prolotherapy.

READ MORE

Ankle Sprain

Ankle sprains are one of the most common musculoskeletal injuries, making up 85% of ankle injuries and 15-45% of all sports related injuries (Bleakley et al., 2010; Ferrn et al., 2006).

READ MORE

Meniscal Tear

A meniscus tear is a rupture of the cartilage within the knee joint. The meniscus is the most commonly injured structure in the knee and usually occurs following a traumatic injury or degenerative changes within the joint (Shiraev et al, 2012).

READ MORE

Subacromial Impingement Syndrome

Research has shown that subacromial impingement syndrome (SIS) of the shoulder joint is one of the most likely causes of shoulder pain.

READ MORE

Prolotherapy for Knee Osteoarthritis in Recent News

A sugar solution injected into the knee could be a new way to treat osteoarthritis. Research suggests that the sugar and water mixture reduces pain and stiffness by stimulating the body’s natural repair mechanisms.

READ MORE

Headaches Arising from the Neck (Cervicogenic)

A Cervicogenic headache is a unilateral or bilateral pain localised to the neck and occipital region which may project pain to the head and/or face.

READ MORE

Cervicogenic Headache

Cervicogenic headache is defined as unilateral or bilateral pain localised to the neck and occipital region which may project to regions on the head and/or face.

READ MORE

Subacromial Impingement Syndrome

Research has shown that subacromial impingement syndrome of the shoulder joint is the most likely cause of shoulder pain.

READ MORE

Interview with Dr Petrides by the British Osteopathic Association

In the Spotlight with Dr Simon Petrides MB BS DO DM-S Med Dip Sports Med FFSEM (UK&I)

READ MORE

‘Neurogenic Hamstrings’ – not just found in footballers! Are Caudal Epidural Steroid Injections useful in rehabilitating hamstring injuries?

‘Neurogenic Hamstrings’ – not just found in footballers! Are Caudal Epidural Steroid Injections useful in rehabilitating hamstring injuries?

READ MORE

Prolapsed Disc

Various things may trigger the inner softer part of the disc to prolapse out through the outer part of the disc.

READ MORE

Shin Splints (Medial Tibial Stress Syndrome)

he most common cause of shin pain is Medial Tibial Stress Syndrome, which is when the muscles, tendons and bone at the shin are not strong enough to withstand the load placed upon them.

READ MORE

Sacroiliac Joint Dysfunction and Pain

Patients with Sacroiliac joint dysfunction can feel pain in the lower back, buttocks, groin and thighs, however it does not typically radiate below the knee.

READ MORE

Prolapsed or Herniated Discs in the Lumbar Spine

A Prolapsed or Herniated disc occurs when the jelly-like center (nucleus) pushes against its outer ring (annulus). This may initially cause a bulging of the outer annulus of the disc, called a Bulging disc.

READ MORE

Prolapsed or Herniated Disc in the Neck

A Prolapsed or Herniated disc occurs when the jelly-like center (nucleus) pushes against its outer ring (annulus). This may initially cause a bulging of the outer annulus of the disc, called a Bulging disc.

READ MORE

Neck Muscle Strain or Spasm

Neck muscular strain can happen suddenly in a traumatic event such as whiplash or it can occur due to strain over time such as bad posture.

READ MORE

Tennis Elbow, New Treatments

Tennis elbow is the most common overuse injury of the elbow and is caused usually by repetitive contraction of the extensor muscles of the wrist.

READ MORE

Pelvic girdle Pain (PGP)/ Symphysis Pubis Dysfunction (SPD)

In the UK it is estimated that one in five woman suffer with Pelvic Girdle Pain (PGP) during or after pregnancy (The Pelvic Partnership Charity).

READ MORE

Pelvic Girdle Pain

A recent article in the Daily Mail (04/07/2012) has highlighted the problem of ‘Pelvic Girdle Pain’ otherwise known as PGP or Symphysis Pubis Dysfunction (SPD).

READ MORE

Spinal Stenosis

Although the cause of spinal canal narrowing may be multi-factorial, there are two types of spinal stenosis, ‘congenital’ meaning from birth or ‘acquired’, found later on in life.

READ MORE

Plantar Fasciitis

Plantar Fasciitis is the inflammation of your plantar fascia. The Plantar Fascia is a strong band of tissue (like a ligament) that stretches from the heel to the base of the toes.

READ MORE

Iliotibial Band Syndrome

Iliotibial band (ITB) syndrome generally presents as a pain on the outside aspect of the knee that gradually increases over a few days to weeks.

READ MORE

Patellofemoral Pain Syndrome

Patellofemoral pain (runner’s knee) is the most common overuse injury among runners. It is the term used by medical practitioners when pain occurs at the front of the knee around the patella (kneecap).

READ MORE

What Can I Do To Help Ease My Neck Pain?

Neck pain is a common problem affecting around two thirds of people at some time in their lives.

READ MORE

Osteoarthritis of the Spine

Osteoarthritis (OA) also known as “wear and tear” is the most common form of arthritis. It usually develops in people aged over 50 and is more prevalent in women than men. It can develop at any age and is most frequently seen in the knees, hips, spine, hands and feet.

READ MORE

Neck Pain – How Can We Help?

Physiotherapists, Chiropractors and Osteopaths are able to provide manual therapy treatments for neck pain. In-line with recent evidence reviews, our practitioners provide mobilisation, manipulation, massage techniques and exercises specific to each individual case.

READ MORE

Whiplash – Not Just From Cars

A whiplash injury can result in a neck ‘sprain’ when your head is suddenly jolted backwards and forwards in a whip-like movement, or is suddenly forcibly rotated.

READ MORE

Common Causes of Neck Pain

Neck pain is very common, it is one of the most common complaints we see as musculoskeletal clinicians . About 2 in 3 people develop an episode of neck pain at some point in their life.

READ MORE

Cervical Facet Joint Syndrome

The cervical facet joints are the joints at the posterior (back) aspect of the spine. Each vertebra in your spine has four facet joints, an upper and a lower pair. These joints link the back of the spine together.

READ MORE

What Can I Do To Help Ease My Lower Back Pain?

Low back pain is a common problem affecting around 4 out of 5 people at some point in their life. Anyone can experience back pain, and at any age. However it is most prevalent in people aged 35, 55 or over.

READ MORE

Hip Joint Injections

Where patients either have suspected or proven pathology inside the hip joint, intra-articular injection of the hip may well prove beneficial.

READ MORE

Spondylolisthesis

The building blocks of a human spine are bones called vertebra. A human spine is made up of 33 vertebrae; 24 are mobile and 9 are fused.

READ MORE

Blackberry Clinic at the Olympic Games 2012

Simon Petrides, Louise Allison and Alice Church have just returned from doing their stints at the Olympics as Games Makers. 

READ MORE

Ferdinand and Vidic attend Blackberry Clinic

England defender Rio Ferdinand and his Manchester United teammate Nemanja Vidic have visited the Blackberry Clinic, a specialist sports clinic based in Milton Keynes, in a bid to save their top level football careers.

READ MORE

Blackberry helps former England keeper, Chris Kirkland

The former England international goalkeeper Chris Kirkland has been receiving treatment at the Blackberry Clinic, in a bid to rid himself of the back problems that have plagued his professional footballing career.

READ MORE

Osteoarthritis of the Knee

Following our management plan could help you go about your daily business without being effected by osteoarthritis in the knee.

READ MORE

Back Pain Doctors

Back pain can be caused by a wide variety of factors, which means that the doctors who treat it often come from many different fields within medicine.

READ MORE

Prolotherapy Injections

After the treatment of prolapsed discs or chronic back pain, instability may be a significant cause of recurrent problems. The use of prolotherapy reduces the risk of recurrence and helps people return to activities faster.

READ MORE