We are Back, Muscle and Joint Specialists. We accept all patients, self paying and insured.

Prolotherapy

Prolotherapy injections work by stimulating the body to make new collagen fibres that are laid down within the substance of the ligaments, thickening and strengthening them.  The solution injected is hypertonic dextrose or occasionally a solution is used containing dextrose, glycerol and 1% phenol. The solution provokes inflammation which attracts collagen producing cells, resulting in a thicker and healthier collagen fibres. This strengthens the ligaments and stops them from being too loose, stabilising the spine or peripheral joints injected.

Prolotherapy injections work by stimulating the body to make new collagen fibres that are laid down within the substance of the ligaments, thickening and strengthening them.  The solution injected is hypertonic dextrose or occasionally a solution is used containing dextrose, glycerol and 1% phenol. The solution provokes inflammation which attracts collagen producing cells, resulting in a thicker and healthier collagen fibres. This strengthens the ligaments and stops them from being too loose, stabilising the spine or peripheral joints injected.

Conditions treated with Prolotherapy

Prolotherapy is used to treat ligaments that have become loosened or stretched from over use or injury or as a result of a physical condition such as Ehlers Danlos Syndrome.  Ligaments provide stability to joints and if they become loose the joint can become unstable and painful. Prolotherapy is appropriate for low back pain and for many other joints in the body such as the knee, shoulder or ankle. At Blackberry Clinic we have had some success with patients with Ehlers Danlos syndrome, alleviating the symptoms of joint hypermobility.   The injection  solution used is used widely in America and is produced by licensed manufacturers in the UK. There is clinical research that endorses its safety and effectiveness as a treatment. For further information see our FAQ’s or please ask the doctor during your consultation.

Patellar Tendinopathy

The patellar tendon is located just below the kneecap. It connects the kneecap or patella to the tibia (shin bone). The quadriceps tendon inserts into...

Quadriceps Tendinopathy

The quadriceps tendon attaches your quadriceps muscles to your kneecap (patella). It works to straighten your knee and helps you walk, jump, and climb...

Ankle Sprain

Most ankle sprains involve injuries to the three ligaments on the outside of your ankle. Ligaments are tough bands of tissue that stabilize joints and...

Meniscus Tear

A meniscus tear is a rupture of the cartilage within the knee joint. The meniscus is the most commonly injured structure in the knee and usually occur...

Patellofemoral Pain Syndrome

Patellofemoral pain syndrome is a dull aching type of pain at the front of the knee, around the kneecap (patella). It is also known as ‘runner’s knee’...

Discogenic Low Back Pain

Discogenic back pain is caused by one or more of the intervertebral discs. It accounts for 39% of chronic low back pain. The intervertebral discs have...

Degenerative Disc Disease

Disc degeneration is one of the most common cause of back pain. Disc degeneration involves a structural, functional, mechanical, nutritional and chemi...

Snapping Hip

Snapping hip is a condition resulting in a snapping feeling when the hip is flexed or extended. There may be a snapping or popping feeling along with ...

Wrist Sprain

A wrist sprain is when the strong ligaments that support the wrist get over stretched, over used or forcibly stretched or bent such as in a fall to th...

Whiplash

The term “whiplash” was first used in the early twentieth century to describe the particular mechanism of injury to the head and neck during a sudden ...

Thumb Sprain

A thumb sprain is when the ligaments that support the joint of the thumb become overstretched or tear due to traumatic injury such as a fall or sudden...

Thoracic Back Pain

The thoracic spine connects with the cervical spine above and the lumbar spine at the base of the spine and is attached to the rib cage. Thoracic back...

Tennis Elbow

This is similar to golfer’s elbow.  However, tennis elbow causes pain around the lateral epicondyle (the outside of the elbow).  It causes pain where ...

Tendon Injury

Tendons are tough fibres that connect the muscles to the bone near the joints.  Most tendon injuries occur near the joints. Tiny tears in the tendons ...

Stress Fracture

Stress fractures are tiny cracks in the bone. They are usually caused by repetitive force such as running long distances or jumping up and down.  Howe...

Spinal Stenosis

Spinal stenosis occurs due to the abnormal narrowing of the space in the spinal canal, which can be caused by either bony or soft tissue encroachment....

Slipped Disc

This is also called a prolapsed disc, herniated disc or disc protrusion. A disc is made up of a softer centre, and a tough fibrous external ring. In s...

SLAP Lesion

A SLAP tear or SLAP lesion is an injury to the glenoid labrum. This is a cartilage structure that surrounds the ‘socket’ of the shoulder. SLAP means, ...

Shoulder Dislocation

The shoulder is the most common joint in the body to dislocate. It occurs when the ball and socket joint of the shoulder come apart. The shoulder can ...

Shin Splints

Shin splints is the term for lower leg pain occurring below the knee, either on the front of the leg or the inside of the leg. This pain often plagues...

Sciatica

Sciatica is pain that radiates from the lower back, through the buttocks and down the back of the leg – following the course of the sciatic nerve. It ...

Sacroiliac Joint Pain / SI Joint Pain

The sacroiliac joints connect the sacrum (the wedge-shaped bone at the bottom of the spine) to the iliac bones (the two bones that make up the pelvis)...

Rotator Cuff Injury

The rotator cuff is a group of tendons connecting the four muscles of the upper shoulder to the upper arm. They run under the acromion where they are ...

Pubic Pain / SPD

Symphysis Pubis Dysfunction is a group of symptoms that cause pain in the pelvic area. It usually occurs after pregnancy and in the front or the back ...

Post Hip Replacement Pain

Hip replacements are amongst the most successful orthopaedic surgical procedures for arthritic hips, but not everyone is pain free after the procedure...

Plantar Fasciitis

This is one of the most common causes of heel pain. It is a disorder of the connective tissue (plantar fascia) which supports the arch of the foot. It...

Pelvic Girdle Pain

Pelvic girdle pain (PGP) is the term now being used by the medical community to describe what was previously known as symphysis pubis dysfunction (SPD...

Osteoarthritis

Osteoarthritis is the most common form of arthritis. It occurs due to the breakdown of joint cartilage and the underlying bone. Osteoarthritis commonl...

Neck Pain

Neck pain is very common. Most people will suffer from one or more episodes of neck pain during their lives. It often starts suddenly and gets better....

Low Back Pain

The lower back is a complex structure of bones, ligaments, muscles and tendons which all work together to provide the low back with support, strength ...

Ligament Injury

The ligaments hold the joints in a stable position and they can get stretched, torn or ruptured in an injury. The knee and ankle are particularly pron...

Knee Pain

Knee pain can be due to a number of causes. It may come on gradually from overuse or unaccustomed activity or be a sudden onset from a fall or sports ...

Joint Instability

Instability happens when tissues such as ligaments and muscles weaken and they cannot stabilise the joint in its proper position. Joints need to be mo...

Hypermobility

Hypermobility refers to joints which have more range of motion than the average. This is commonly known as being double jointed.

Hip Pain

The hip is a ball and socket joint and is very strong and stable. It is supported by a strong network of tendons, muscles and ligaments. Hip pain is a...

Hamstring Strain

There are four hamstring muscles attaching the pelvis to the knee. A strain of these muscles can range from mild to very severe involving complete rup...

Groin Strain

A groin strain is an injury to the muscles on the inner side of the thigh, known as the adductor muscles. This type of injury can be very painful and ...

Golfer’s Elbow

This is similar to tennis elbow.  However, golfers elbow causes pain around the medial epicondyle (the inside of the elbow).  It causes pain where the...

Foot Pain

The foot is made up of a complex network of bones, ligaments, muscles and tendons, designed to give you both stability and mobility. Therefore, there ...

Elbow Pain

The elbow is a complex joint, allowing both flexion and extension, as well as rotation of the forearm.  There are many muscles, ligaments and tendons ...

Arthritis

There are many different types of arthritis, with the  the two most common types being osteoarthritis (wear and tear) and rheumatoid arthritis. Osteoa...

Ankle Pain

The ankle is made up of many bones, ligaments, tendons and muscles designed to give you both mobility and stability. There are many different structur...

Achilles Tendonitis

The Achilles tendon is located at the back of your ankle and connects your two calf muscles to the bone in the heel of your foot. The tendon is made u...

AC Joint Sprain

This is the small joint between your collarbone (clavicle) and your shoulder blade (scapula)and is  known as the acromioclavicular joint. A sprain can...
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Treatment for acute and chronic sports injuries, arthritis, soft tissue injuries and exercise medicine consultations

Our Prolotherapy Clinicians

Musculoskeletal, Sport & Exercise Medicine Specialist
Musculoskeletal and Sports Medicine Doctor
Pain Medicine Consultant
Consultant in Sport, Exercise & Musculoskeletal Medicine
Sport & Exercise Medicine Consultant
Sport and Exercise Medicine Consultant
Sport and Exercise Medicine Doctor Musculoskeletal Medicine Doctor
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Frequently asked questions about Prolotherapy

You will have a thorough assessment to see which treatment is appropriate and the treatment will be explained to you.  You will be taken to our fluoroscopy theatre so the doctor can use the x ray or ultrasound equipment for guidance in placing the needle. The doctor will explain what is happening throughout the procedure.

A local anaesthetic will be used to reduce the pain and there are other methods of pain relief available if necessary.  These injections do cause some aching and stiffness for one to two days. The benefit is gradual and should be optimal after 6-8 weeks.

Prolotherapy is a course of three injections at intervals of between one to three weeks. A second course can be used if there is a significant but incomplete effect from the first.

Our Musculoskeletal (MSK) Doctors are experienced in these injections. See below for Doctors who offer these procedures and the Clinics where they work.

Please make a double appointment (same cost as a single consultation) with the doctor who you have been referred to (costs are available here)  He/she will then take a history, examine you and make a diagnosis and recommendation. He/she can also write to your GP.

If Prolotherapy is determined to be the appropriate course of treatment then you will need to make 3 further appointments at weekly intervals at a cost outlined here.

The injections are done under x-ray guidance and take about 3 minutes within your 30 minute appointment (Sometimes, if the pain is severe, he/she may advise a cortisone injection first which costs from £500 depending on the site. You will then need to leave 2 weeks before starting prolotherapy)

We hope that answers all of your queries. If not, please contact our theatre staff at the clinic in Milton Keynes on 01908 604666.

Please bring  the most recent MRI scan and report if possible

The use of hypertonic dextrose solutions to treat lax ligaments and instability of any joints in the body. Platelet Rich Plasma and Stem cell therapy also count as prolotherapy since the result is a ‘proliferation’ of normal body connective tissue and collagen found in ligaments and tendons.

A standard set of prolotherapy in the UK is three injections but if there is considerable improvement and the improvement is incomplete then a further three injections are frequently offered.

On average, patients experience one year of improvement and relief from prolotherapy. However, there is a huge variation and sometimes improvement lasts from three months to 15 years. A repeat course of injections is often indicated and produces a similar period of relief.

We do not offer intravenous sedation but we do have Entenox gas,  a mixture of nitrous oxide and oxygen,  which provides an element of pain relief and sedation. Some patients who are already taking muscle relaxants such as Diazepam can take a tablet prior to one hour before their treatment. Most patients do not find that either of these measures is necessary since the discomfort is usually tolerated sufficiently.

About 80% of patients experience at least a 50% improvement in the symptoms.

If you call the Blackberry  Clinic of your choice you will find that most appointments are available within the week depending upon your own availability

Yes, but the fluoroscopic x-ray is extremely low dose, you get more radiation on a transatlantic flight! For accuracy we use fluoroscopic x ray.

There is minimal danger to the sciatic nerve. The risk may be more if the injection is done without x-ray guidance. There is 1:7000 chance of allergy, infection bleeding or nerve damage as with any spinal injection.

Around 14,500 over 32 years

Around 80% of patients.

Yes, we use a number of different solutions and techniques depending upon the problem being treated. Commonly used preparations include:

Dextrose: 5%. 15% and 25%

P2G: which contains dextrose 12.5% glycerol 12.5% and phenol 1%.

Posterior SI ligaments, interosseus and occasionally sacro-tuberous and sacro-spinous ligaments.

Currently Blackberry Clinic Milton Keynes and Blackberry Clinic Oxford.

Prolotherapy can be used to treat the spine including lumbar, thoracic and cervical spine up to the level of C2 but we do not use this treatment any higher.

We can treat osteoarthritis of the knee and hip along with recurrent ankle sprains and shoulder instability or rotator cuff tendinopathy.

There are too many areas of the body to list here and it is worth a consultation to discuss your options.

For a standard set of 3 injections (done on three appointments from 1-4 weeks apart) the cost is £500 per treatment so a standard set is £1500.

In private hospitals these types of injections can cost significantly more!!

Yes, for safety and accuracy whilst maintaining the comprehensive nature of the treatment.

1-4 weeks depending on the problem

There is no limit, but if you needed more than 3 courses in a year you may have to reassess the appropriateness of the treatment.

Yes, our theatre staff will assess you after the treatment and so long as you are feeling fine they will let you go within 20 minutes of finishing the procedure.

Yes, so long as you were doing those things before the injection without much discomfort. We like you to avoid provocative activity (ie activity that usually caused your pain) until 3-4 weeks after the course has finished.

Yes, so long as you were doing those things before the injection without much discomfort you can start these activities again shortly after your treatment. Check with the nurse or doctor.

Yes, please stop non-steroidal anti-inflammatory medication such as Nurofen, Ibuprofen, Naproxen and Diclofenac on the day of the procedure and do not resume until after the course has finished. Please discuss with the doctor at the first appointment. We suggest you stop Turmeric too.

Usually one area of the body is treated at one visit.

Both sacroiliac joints can be treated on the same visit, this can include the lumbar spine also.

No more than 3 levels of the lumbar spine are treated at one visit.

A short letter from the podiatrist would be fine.

It is guided by fluoroscopic x-ray for safety and efficacy, there is no need for contrast/dye.

We assess the full effect 4-6 weeks after the last of the three injections. However some patients feel a beneficial effect after the first injection.

The frequency of subluxation/dislocation should diminish as you progress through the process.

The waiting list can be 1 day to 2 weeks depending on various circumstances but it is worth calling to find out the current wait.

1/7000 chance of allergic reaction, infection, bleeding or nerve injury which is similar to any spinal injection.

1/7000 chance of allergic reaction, infection, bleeding or nerve injury which is similar to any spinal injection.

The pain can feel worse for a day or so after the injection.

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