Prolotherapy 3

State of the Art Prolotherapy Theatre

Prolotherapy 1

Sclerosant Injections to Ligaments

Prolotherapy 2

Reduces the Risk of Recurring Back Pain

Prolotherapy 4

Neural Prolotherapy

Prolotherapy Research

Scientific Research - 1 of 2
Dextrose prolotherapy is an effective treatment option in patients with chronic, recalcitrant coccygodynia and should be used before undergoing coccygectomy. Randomised studies are needed to compare prolotherapy with local steroid injections or coccygectomies.

Klein RG, Dorman TA, Johnson CE. Proliferant injections for low back pain: histologic changes of injected ligaments and objective measures of lumbar spine mobility before and after treatment. J Neurol Orthop Med Surg. 1989; 10: 141-144.
Cusi M, Saunders J, Hungerford B et al. The use of prolotherapy in the sacroiliac joint. Br J Sports Med. 2010; 44(2):100-4.
Liu YK, Tipton CM, Matthes RD, et al. An in situ study of the influence of a sclerosing solution in rabbit medial collateral ligaments and its junction strength. Connect Tissue Res. 1983; 11:95-102.
Centeno C. Fluoroscopically guided cervical Prolotherapy for instability with blinded pre and post radiographic reading. Pain Physician, 2005; 8(1): 67-72.
KhanSA, KumarA, VarshneyMK, TrikhaV, YadavCS, Dextrose prolotherapy for recalcitrant coccygodynia. Journal of Orthopaedic Surgery, 2008; 16(1): 27-9.

Scientific Research - 2 of 2
Injection therapy of painful enthesopathies can provide significant relief of axial pain and tenderness combined with functional improvement, even in failed back syndrome patients. Phenol-glycerol prolotherapy provides better and longer lasting relief than injection with anaesthetics alone. Prolotherapy provides over six months of relief for some patients but generally provides relief for only a few months. However, most patients who described good to excellent relief felt that the injections had been beneficial, and requested additional injections for recurrent or residual focal pain.

. Injection therapy for enthesopathies causing axial spine pain and the failed back syndrome: a single blinded, randomised and cross-over study. Pain Physician, 2005; 8(2): 167-7.